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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3b9db20ec2b702d6e1ad020eb98c135a4eca7724d300b7fe7ea98cb062e3d3' 
  AND token = 'IM8/+INKQXE1/HUGOBgxnq2Mm1CGD5ZubjhK9gtkJLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}