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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a4a965bcf4c0d8244a455a670aa23a3acf7a19ad3bf4cfe9186d889b473c1b' 
  AND token = 'C6Lf/gIEnxvgp6nBnp01gJIiPahwk09SRMPdBJUyUu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}