SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab3875012c6d7dca99b89a6801be4668520c8ff0eeef2bbd191f6d1921bd151' 
  AND token = 'ec7ww2NsLXsQ0B6Z23AKvrWnE+cbgGLAyZoWYMCM/qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}