SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bc518c4a8c3a0c55aaa9f6d1a2349d3844c968be1e089f45945be6452dbe3f' 
  AND token = '5+dKAsnk/I35Mkixqt/SEoFKXY5e6MMOTlKJ1R4P9Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}