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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20179c6e3ed9febff5b130ece01a1b57445b6536ff22fef6dbaef29c6e206a72' 
  AND token = '/tMiO5OTWcoCIWBjaO8Sjqc7qyYdqYmR+1LnrWZIOqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}