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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46980be22b41b43d215730c6d1e6d0309468def2fad5e71e810bfadee609ce71' 
  AND token = 'N8020LMddjc9WwMZN1xcSZjwZq7qSHBp+x2bZ7M+8pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}