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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de43e013a5cd772f0d0c2d4d555c8d3818ba64f5e5057af35700b83ed01806d9' 
  AND token = 'IG1l22rDKKjDalIClgFOq5WhYZ4ZRE0mL1ON1y1aR+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}