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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a5959a6e34719fa2eba18fb8dc3831d944ef4c87f8918ce9e7e57d4c19961df' 
  AND token = '8TPgeKNX3mMKa0V3Je0tJ/x2mVmTS2k0UPUFD5cQkWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}