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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac8986a4e9e4534617b0fbfdd8928cce4dcfaf5729be57f8a5ebba4fa89ab8e' 
  AND token = '1/BxSIZDII8dGe++cuIAIhc7OGFOzqL729tM9OsnxU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}