SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4efc3ef9ebb11457ce4d656aa5fe43d5c6e75f80ee11e97d8653afb5854980' 
  AND token = 'QyvWGwfCDEkgq4ENqUUm4Ov+71ufdERzNr0g5fjRlAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}