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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80de32e75fdefe3e50f76029173f2e28f7e8ac9acae7c7735f9e92a7e611f3c7' 
  AND token = '7CBknRm80RxCbBz49WB6XVVGOvsKN50rfCgAsIEpfec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}