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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f257553a44e50a15357e9fee1e2f76f0cbb3846dcb0ae39da04863336fbaa6ab' 
  AND token = 'KR6ilQPl3mn2RPkQenVcsL8uwWoElcRBX++SCG9cw/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}