SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85f5cee3bce5110675f6dcb2ff1e7748037e93c2a4194f237f024e2c19df53eb' 
  AND token = 'lbalPUsgMreqfSvkaNBr8y4qrNe+o8ud8TZOxTUGOuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}