SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78254ec2a1f900b22e8ae190e738c2b1e5d571831b9c81dbb397829236d25d8e' 
  AND token = 'g/Hy+0Hg0ndx35QflHJh0BUwLFfia1OV6YZwkcKzA2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}