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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fda005d53b2c4768a2f370b86aa86fd74d0bd6c8913c839ac45c73d17ece981' 
  AND token = 'esdzvyYLQLPVk2cub0aJ1GoB9rSNVEQzA3tLrkwUb0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}