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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4765fb8aec9a571650a65e6d9a3b1ad792c8616c20ee21fbebcd2763db2da5f9' 
  AND token = 'VxwoeckyidIZu0uCCpkLCDr9Kg2S9Uh3tgg7bgZAxWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}