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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f20482ef2b83c84731c7b21f4379b1304f60250d37a9098a1c9c40182f8201c' 
  AND token = '27ypnOy5Meb+2ee46fGO2cr/qEQn7f0GJ/fsTgi6Dhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}