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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563ea9bd4eb4e5c527ee6235721e6c9df0dd4b39c1dcb00593cc183e40e41a93' 
  AND token = 'JailSSKXJXENsBmVsEtxft4cp8zh0njFqPPl+Xb9GG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}