SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e2e2bf05498bdaf681d261257ce947f1501cfb395e4397bfd09a9eefd6280d' 
  AND token = 'jZCw2FekskWtKF9e11XVVSqRiPJw8fOKT6E8/YfBjUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}