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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f064b48e00a9f50362cdb4c31c18b55ed51b159c58fb8e79799af1d185742b0' 
  AND token = '557Jce13VVqX5mPLIB4XnhA5+kjRMQwypDmpvc4oHao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}