SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fb28edb7487739b142ccbb61463d721c6c6dea9f955a39e49dc87b85e58fc5' 
  AND token = 'xp8888cMyJoaUPm+FQoW2UuFDXeT0PcqnsfnWngWjo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}