SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a408a0194a6e8393e6b00a221029282c3e80d19bd04a07876fe1a261c8b64a8c' 
  AND token = 'VWLdRNCNIWET8zClxlzZ/v81+Btz3HmW8pi3ooEFP1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}