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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0cf076b89ec894b10d21aec77cd0b622610f7b6486680b47da6a4bb9f524bd' 
  AND token = 'RLJLURk6Ex9lDfRVbpZRRdl7/djE7bADjLW8KveELVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}