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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e7bd0adf49191fd221a70d4a9f1bdfe0065196da48659921ddc3e2e0ab643d' 
  AND token = 'Id9P4Ssp8a6fcN36blfaXPyCGCODfHKGB7cWmt3oJKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}