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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a410c81b50b236798ff3cacd0208ead8d5b3012283bad0cf048a38d19b5d08fb' 
  AND token = 'pc6GUbJakAuUqhhCPcgDY5GGHXRL6+JzOKhNM3kBhTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}