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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621497617fb672fc8345b555eabb579b6dedc2d317ab80ceb547ef4f8b62f3fd' 
  AND token = 'nLz1Hz1cloD1LxdZqYDuflX7Wf4B5bPNPGKsayZ0C/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}