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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56de66c716c4c19f943179f08d47dd5d0d51db7c70793f5fd3f1bf9767b80322' 
  AND token = 'R+KBSUz/jJCUgKsfm9pkUa1cLfTHRmm1/jT1/TNIYdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}