SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a63f05c15131662202bd4c657a977c16e2761835a7d24171617862ac8da8b9f' 
  AND token = 'MNapkDmU+K8phcjYXIq8vh2SmZHZvK8RxTXOHHYO820=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}