SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f17ddebbdbd91f5d6a1d02c3756a61a16d9f357ac8b766e2e3b747724ec04235' 
  AND token = 'vH3miN63Vuhx2UuNlZeSOWk/JOg8iqNU1YyVOE0kn7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}