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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33210d517a0d43176c3c386e3f5397d24300338f5154fd8ff7bea0d6a2fcec12' 
  AND token = 'TH7/tIGBXVIOnA1DKU76D0yTTcKLJwGwmU8ZP8P6cOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}