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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745fb11d0fdbd07ef699d89838288a92eb9a853d4c73fa524ccf38f9f28cb55b' 
  AND token = '6ZWwSK7c6b3BvSyirvkw2Wuit9UKKCuT+KKK2eu/u0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}