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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1bf9599a11d2a3b39e7d7c7b630f8d66d88bb2f24e9f8d9682af1dd110ad1ea' 
  AND token = 'T+NYQ4HS8fnTmguAy307j6CodKxLu9jeNpJ3JTzstzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}