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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19b043b2db85f338ee380f573ee7aeb3ecb10a9e71b656d03534a282b14af033' 
  AND token = 'nLC34dN2gA2eHRxWMLcoQy/xt/DVtTZMYls8zSxynOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}