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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4148ec84d0105e8c117fbb2018b3ebf00a074c4b90a05bf48b0401def6bf0986' 
  AND token = 'KqRlmPu3t5T8TFvPdEFYeCTUHugWRf+dZaL/Qn5UsiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}