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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dde703af873bd32c0e14d2ed5250fc319750abb7e3f18a422d9fd99c1c276d7' 
  AND token = 'JIas6MvRn2sUaf5AjQ/yhcUVBxrnlcKJ0g1rHC+TPDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}