SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353f1b54bdb968ede326d03f233777583218afec1fb7d278e3cdd7aaec97d035' 
  AND token = 'kPKtlNdSwnR/0NmXxgDHo+evaeCZ/EijlO2TDetFefA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}