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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4851528c52869900d78b6e06a24c330ad5d9af483a3e64ebc88a4a2dd483768f' 
  AND token = 'EgePqbZAVl3Xo/dfOQ+mMXu/ynpV+bD/3qnXllQI5ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}