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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b0a11e98debe2da8c522207b59516268e7267200cd8b4b20015f4fa039f78c' 
  AND token = '8zpdN+qiZqqdZL5XMAycAHZaYSZn+mxlmiPgnMy3n8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}