SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8845594903afd1ddbf763af4b90f8e46b80e66f9b305c463553de28852c4c88' 
  AND token = 'rjQ5IT6rjBwlqpDtEwBT/6SIwa5vKrZrh6X+qsOW4dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}