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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27fbc54444657a3ddb111a2d3f8dfab34c6cce277c1d69cbe5b9d5c2983db579' 
  AND token = 'owpwcihkduYighJG3/pscX6SCjUYTn6Dm57dZr0tQQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}