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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'affc314b18fb10c5d9c598e253f45b0fb09aaee6fb60efb3b4fe00af7d41cb35' 
  AND token = '3ZvH7SxkUrMVtXDnJwgrG1Whq63G8ZhwQJMoTzm0AOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}