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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9465e041487ad87ffba4124ed8ca94c28bf980a3215b6acf8b8f9370442417c8' 
  AND token = 'y/qSPSqLm7QO9fNGTaRZLi57LkyadCJLgA2H/KC9afU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}