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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241bfeea04d26eab7966939a1135942893a18a74f5d039ab3a4025361a322c25' 
  AND token = '0ktIdx+HBlhmhR4rTwB7KJBOXy3OmF53nCxgcH6d93U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}