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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e28da4850995664b3e0e65c8249713cd2ea2f6d9fd7f9850d90bdaf6d1e96a' 
  AND token = 'VxsTRBO9DLmV4sF86iZwqSSFOA9fP/iQ7QCCV5DtejA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}