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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b1943a68dfc4e5d7e952ebfac5f188eea1080450f0635133606b466b9c81c8' 
  AND token = 'RUiX5m9QhCfOH1khp7RKqPW2I4mvRLOk9rzvZLTEPIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}