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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446a9d109b92c802114f81ec78643da5c87055d1f7880e3f38300af04a3c7813' 
  AND token = 'PL36hZL3RlB423X4dyjARNmPKGrgXR0dxfJKd9DZMtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}