SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9ed5ade99035fa64d32aeb64fb38151a4d4cab6cf60c1c454f52601c43f19b' 
  AND token = 'uNVy3wkZwZrZSuICKPlVWYKH6dZjoEYNcnI+8QAl+aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}