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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '206a31a2f35489b840458830ffee30841c7b606e7730ba9f855d79aaae4bbf17' 
  AND token = 'CQs7I2OrfzcxU58ZwqKrmfPEfDu+UShEA8QXmwS/SwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}