SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2961445321794e05e845e6a2cb657c6ffb1798e426de9bdec916582042d3ce20' 
  AND token = '0WGBCstxTw0D9EwmlPBwv8Ju54YWUEJ2vgR2p1E8jMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}