SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7636620e91a14b3419e8be1f319ebd3e62c0a30fdd770731cb25b065712bfc89' 
  AND token = 'eH4Azj2nG4IiIijlZJ9GVTKLiXd+sADLDvu0pH2DIVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}